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Christian Louboutin Outlet We investigated the association between cured meat intake and worsening asthma symptoms in adults, and the role of BMI as a potential mediator.Methods Using data from the French prospective EGEA study (baseline: 2003 2007; follow up: 2011 2013), we applied a mediation analysis in the counterfactual framework, a marginal structural model (MSM), to estimate the direct effect of baseline cured meat intake (Results Among the 971 participants (mean age 43years; 49% men; 42% with asthma) Cheap Christian Louboutin Shoes louboutinshoecheap.com, 20% reported worsening asthma symptoms during the mean follow up time of 7years. Using the MSM, we reported a positive direct effect of cured meat intake on worsening asthma symptoms (multivariable OR=1.76, 95% CI 1.01 to 3.06 for 4 vsConclusions Higher cured meat intake was associated with worsening asthma symptoms over time, through a direct effect and to a lesser extent an effect mediated by BMI. This research extends the effect of diet on asthma in adults.FootnotesRN and RV contributed equally.Funding This research was funded in part by Merck Sharp Dohme (MSD), the GA2LEN project, Global Allergy and Asthma European Network, and Conseil scientifique AGIR pour les maladies chroniques, National Hospital program of clinical research (PHRC national).Competing interests None declared.Ethics approval Ethical approval was obtained from the relevant institutional review board committees (Cochin Port Royal Hospital and Necker Enfants Malades Hospital, Paris) Christian Louboutin Outlet.
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